1. Try to manage as much as possible using your web-based control panel
2. Configure DNS time-to-live and other settings to fit your objectives
3. Assign domains that do not need their own IP addresses to shared IPs
4. Use the DNS CNAME function to point several versions of a domain to the same IP (i.e. domain1.com, domain1.net, domain1.org)
5. Use sub-domains only when necessary. Otherwise, use sub-directories
6. Be sure to delete any hosting entries for domains that you do not intend to renew